Heterocycles

A simple method for the synthesis of 1-Substituted β-Carboline derivatives from tryptamine and carboxylic acids in polyphosphoric acid

I Ivanov, S Nikolova, S Statkova-Abeghe

文献索引：Ivanov, Iliyan; Nikolova, Stoyanka; Statkova-Abeghe, Stela Heterocycles, 2005 , vol. 65, # 10 p. 2483 - 2492

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被引用次数: 13

摘要

Abstract–A number of 1-substituted 3, 4-dihydro-9H-β-carboline derivatives (4) with high purity and yields have been synthesized by treating of tryptamine (1) with carboxylic acids (2) in polyphosphoric acid. 3, 4-Dihydro-9H-β-carbolines (4) were successfully transformed to 1, 2, 3, 4-tetrahydro-9H-β-carbolines (5) and 9H-β-carbolines (6).