1-Hydroxyalkyl-3-phenylthioureas as novel HDL-elevating agents

…, JB Eskesen, DS France, JR Paterniti

文献索引：Coppola, Gary M.; Damon, Robert E.; Eskesen, J. Bruce; France, Dennis S.; Paterniti Jr., James R. Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 3 p. 809 - 812

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被引用次数: 12

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A series of 1-hydroxyalkyl-3-phenylthiourea analogs were prepared and evaluated as HDL-and Apo A–I-elevating agents. Derivatives 5h, 7j, 7n, and 7o were found to be as effective or superior to gemfibrozil (1). ... Thiourea 2 was identified as a potential HDL-elevating agent from a ...