A novel L-amino acid ligase from Bacillus subtilis NBRC3134 catalyzed oligopeptide synthesis

K Kino, T Arai, D Tateiwa

文献索引：Kino, Kuniki; Arai, Toshinobu; Tateiwa, Daisuke Bioscience, Biotechnology and Biochemistry, 2010 , vol. 74, # 1 p. 129 - 134

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被引用次数: 15

摘要

l-Amino acid ligase catalyzes dipeptide synthesis from unprotected l-amino acids in an ATP- dependent manner. We have purified a new l-amino acid ligase, RizA, which synthesizes dipeptides whose N-terminus is Arg, from Bacillus subtilis NBRC3134, a microorganism that produces a rhizocticin peptide antibiotic. It was suggested that RizA is probably involved in rhizocticin biosynthesis. In this study, we performed sequence analysis of unknown ...