Synthesis of 6??Aminopropyl??6H??indolo [2, 3??b] quinoxaline Derivatives

…, NA Kutuzova, AV Mazepa, SA Lyakhov…

文献索引：Shibinskaya, Marina O.; Kutuzova, Nina A.; Mazepa, Alexandr V.; Lyakhov, Sergey A.; Andronati, Sergey A.; Zubritsky, Mykhayl Ju.; Galat, Valerij F.; Lipkowski, Janusz; Kravtsov, Victor Ch. Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 3 p. 678 - 682

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被引用次数: 4

摘要

Abstract A series of 6-(3-aminopropyl)-6H-indolo [2, 3-b] quinoxalines were synthesized with high yields by the reaction of 6-(3-chloropropyl)-6H-indolo [2, 3-b] quinoxaline and corresponding amines in presence of tetrabutylammonium iodide in boiling toluene or dimethylformamide at room temperature. It was found that boiling of 6-(3-chloropropyl)-6H- indolo [2, 3-b] quinoxaline in acetone with sodium iodide or in acetic acid lead to ...