Monoacetyldiglycerides as new Ca 2+ mobilizing agents in rat pancreatic acinar cells

…, SH Cho, SY Kim, JT Seo, SJ Moon, GJ Jhon

文献索引：Han; Cho; Kim; Seo; Moon; Jhon Bioorganic and medicinal chemistry letters, 1999 , vol. 9, # 1 p. 59 - 64

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被引用次数: 22

摘要

Several monoacetyldiglycerides were synthesized from glycerol in search for new Ca2+ mobilizing agent in vitro. All monoacetyldiglycerides except linolenoyl and phenlycyclopropylcarbonyl derivatives showed activity toward Ca2+ release in pancreatic acinar cells. Linoleoyl and docosahexaenoyl derivatives were chosen for further test and exhibited unique activity.