前往化源商城

A Facile and Green synthesis of novel imide and amidic acid derivatives of phenacetin as potential analgesic and anti-pyretic agents

YD Reddy, PP Kumar, BR Devi…

文献索引:Reddy, Yervala D.; Kumar, Padam P.; Devi, Bhoomireddy R.; Dubey, Pramod K.; Kumari, Yalamanchili B. Letters in Organic Chemistry, 2013 , vol. 10, # 1 p. 70 - 76

全文:HTML全文

被引用次数: 6

摘要

Facile and green syntheses of potential analgesic and antipyretic compounds, N-(4-ethoxy- phenyl)-2-(1, 3-dioxo-1, 3-dihydroisoindol-2-yl) acetamide derivatives 6a-g and N-[(4-ethoxy- phenylcarbamoyl) methyl] phthalamic acid derivatives 10a-g have been developed. Two synthetic routes (A and B) have been established for the preparation of 6a-g. In the route-A, 4-ethoxyaniline 2 was reacted with chloroacetyl chloride 3 in a solution of potassium ...