Facile and green syntheses of potential analgesic and antipyretic compounds, N-(4-ethoxy- phenyl)-2-(1, 3-dioxo-1, 3-dihydroisoindol-2-yl) acetamide derivatives 6a-g and N-[(4-ethoxy- phenylcarbamoyl) methyl] phthalamic acid derivatives 10a-g have been developed. Two synthetic routes (A and B) have been established for the preparation of 6a-g. In the route-A, 4-ethoxyaniline 2 was reacted with chloroacetyl chloride 3 in a solution of potassium ...