New nonnucleoside substrates for terminal deoxynucleotidyl transferase: synthesis and dependence of substrate properties on structure

AL Khandazhinskaya, MK Kukhanova…

文献索引：Khandazhinskaya; Kukhanova; Jasko Russian Journal of Bioorganic Chemistry, 2005 , vol. 31, # 4 p. 352 - 356

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被引用次数: 4

摘要

Abstract N-(9-Fluorenylmethoxycarbonyl)-ω-aminoalkyl-, N-(9-fluorenylmethoxycarbonyl)-8- amino-3, 6-dioxaoctyl, and N-[(9-fluorenylmethoxycarbonyl)-6-aminohexanoyl]-2-aminoethyl triphosphates were synthesized. All of them were shown to be the substrates of the calf thymus terminal deoxynucleotidyl transferase. Their substrate properties depend on the length and structure of the linker between the 9-fluorenylmethoxycarbonyl and ...