Molecules

Synthesis of Highly Substituted Oxazoles through Iodine (III)-Mediated Reactions of Ketones with Nitriles

A Saito, N Hyodo, Y Hanzawa

文献索引：Saito, Akio; Hyodo, Nao; Hanzawa, Yuji Molecules, 2012 , vol. 17, # 9 p. 11046 - 11055

被引用次数: 10

摘要

Abstract In the presence of trifluoromethanesulfonic acid (TfOH) or bis (trifluoromethane- sulfonyl) imide (Tf 2 NH), iodosobenzene (PhI= O) efficiently promoted the reactions of dicarbonyl compounds as well as monocarbonyl compounds with nitriles to give 2, 4- disubstituted and 2, 4, 5-trisubstituted oxazole in a single step under the mild conditions. Keywords:

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