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Tetrahedron Letters

Continuous flow biocatalytic resolutions of methyl sulfinylacetates

Z Liu, K Burgess

文献索引:Liu, Zhanxiang; Burgess, Kevin Tetrahedron Letters, 2011 , vol. 52, # 48 p. 6325 - 6327

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被引用次数: 3

摘要

Product inhibition was encountered for some substrates in the resolution of methyl sulfinylacetates mediated by lipase Amano AK, so an apparatus to continually extract the carboxylate product was devised. This was applied to resolve some sulfoxides with high