Tetrahedron Letters

Continuous flow biocatalytic resolutions of methyl sulfinylacetates

Z Liu, K Burgess

Index: Liu, Zhanxiang; Burgess, Kevin Tetrahedron Letters, 2011 , vol. 52, # 48 p. 6325 - 6327

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Citation Number: 3

Abstract

Product inhibition was encountered for some substrates in the resolution of methyl sulfinylacetates mediated by lipase Amano AK, so an apparatus to continually extract the carboxylate product was devised. This was applied to resolve some sulfoxides with high

2365-48-2

Methyl thioglycolate

100-00-5

4-Chloronitrobenzene

~80%

N-Nosyl-α-amino acids in solution phase peptide synthesis

[Leggio, Antonella; Di Gioia, Maria Luisa; Perri, Francesca; Liguori, Angelo Tetrahedron, 2007 , vol. 63, # 34 p. 8164 - 8173]

Sulfonyl esters. V. A preparation of dichloromethyl sulfones

[Langler, Richard Francis; Steeves, Jennifer Lea Australian Journal of Chemistry, 1994 , vol. 47, # 8 p. 1641 - 1646]