NH2-PEG8-OH

Modify Date: 2024-01-04 11:17:23

NH2-PEG8-OH Structure
NH2-PEG8-OH structure
Common Name NH2-PEG8-OH
CAS Number 352439-37-3 Molecular Weight 369.45100
Density N/A Boiling Point N/A
Molecular Formula C16H35NO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NH2-PEG8-OH


NH2-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-Aminooctaethylene Glycol
Synonym More Synonyms

 NH2-PEG8-OH Biological Activity

Description NH2-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C16H35NO8
Molecular Weight 369.45100
Exact Mass 369.23600
PSA 110.86000

 Safety Information

Hazard Codes Xi

 Synthetic Route

~90%

NH2-PEG8-OH Structure

NH2-PEG8-OH

CAS#:352439-37-3

Literature: Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503

~%

NH2-PEG8-OH Structure

NH2-PEG8-OH

CAS#:352439-37-3

Literature: Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503

~%

NH2-PEG8-OH Structure

NH2-PEG8-OH

CAS#:352439-37-3

Literature: Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503

~%

NH2-PEG8-OH Structure

NH2-PEG8-OH

CAS#:352439-37-3

Literature: Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503

~%

NH2-PEG8-OH Structure

NH2-PEG8-OH

CAS#:352439-37-3

Literature: Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503

~%

NH2-PEG8-OH Structure

NH2-PEG8-OH

CAS#:352439-37-3

Literature: Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503

 Synonyms

1-amino-2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Top Suppliers:I want be here


Get all suppliers and price by the below link:

NH2-PEG8-OH suppliers

NH2-PEG8-OH price