Tr-PEG4-OH structure
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Common Name | Tr-PEG4-OH | ||
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CAS Number | 125274-16-0 | Molecular Weight | 436.54000 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C27H32O5 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Tr-PEG4-OHTr-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Name | 2-[2-[2-(2-trityloxyethoxy)ethoxy]ethoxy]ethanol |
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Synonym | More Synonyms |
Description | Tr-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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Related Catalog | |
In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
References |
Molecular Formula | C27H32O5 |
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Molecular Weight | 436.54000 |
Exact Mass | 436.22500 |
PSA | 57.15000 |
LogP | 4.03720 |
~99% Tr-PEG4-OH CAS#:125274-16-0 |
Literature: Bondia, Andrea Molero; Larcher, Nicolas; Garrelly, Laurent; Rossi, Jean Christophe; Pascal, Robert Tetrahedron Letters, 2010 , vol. 51, # 25 p. 3330 - 3333 |
~% Tr-PEG4-OH CAS#:125274-16-0 |
Literature: Breyholz, Hans-Joerg; Wagner, Stefan; Faust, Andreas; Riemann, Burkhard; Hoeltke, Carsten; Hermann, Sven; Schober, Otmar; Schaefers, Michael; Kopka, Klaus ChemMedChem, 2010 , vol. 5, # 5 p. 777 - 789 |
~70% Tr-PEG4-OH CAS#:125274-16-0 |
Literature: Gartiser, Thierry; Selve, Claude; Mansuy, Laurence; Robert, Alain; Delpuech, Jean-Jacques Journal of Chemical Research, Miniprint, 1984 , # 9 p. 2672 - 2691 |
Precursor 3 | |
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DownStream 7 | |
2-(2-(2-(2-(trityloxy)ethoxy)ethoxy)ethoxy)ethanol |
2,5,8,11-Tetraoxatridecan-13-ol,1,1,1-triphenyl |
13,13,13-triphenyl-3,6,9,12-tetraoxatridecan-1-ol |
Tr-PEG5 |
11-(triphenylmethyloxy)-3,6,9-trioxaundecan-1-ol |
1,1,1-triphenyl-2,5,8,11-tetraoxatridecan-13-ol |
13,13,13-triphenyl-3,6,9,12-tetraoxatridecanol |
tetraethylene glycol monotrityl ether |
TrtO-4eg-OH |