Tr-PEG4-OH

Modify Date: 2024-01-10 20:06:40

Tr-PEG4-OH Structure
Tr-PEG4-OH structure
Common Name Tr-PEG4-OH
CAS Number 125274-16-0 Molecular Weight 436.54000
Density N/A Boiling Point N/A
Molecular Formula C27H32O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tr-PEG4-OH


Tr-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

 Names

Name 2-[2-[2-(2-trityloxyethoxy)ethoxy]ethoxy]ethanol
Synonym More Synonyms

 Tr-PEG4-OH Biological Activity

Description Tr-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Related Catalog
In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Zhang Q, et al. Synthesis of a library of propargylated and PEGylated α-hydroxy acids toward "clickable" polylactides via hydrolysis of cyanohydrin derivatives. J Org Chem. 2014 Oct 17;79(20):9546-55.

 Chemical & Physical Properties

Molecular Formula C27H32O5
Molecular Weight 436.54000
Exact Mass 436.22500
PSA 57.15000
LogP 4.03720

 Synthetic Route

~99%

Tr-PEG4-OH Structure

Tr-PEG4-OH

CAS#:125274-16-0

Literature: Bondia, Andrea Molero; Larcher, Nicolas; Garrelly, Laurent; Rossi, Jean Christophe; Pascal, Robert Tetrahedron Letters, 2010 , vol. 51, # 25 p. 3330 - 3333

~%

Tr-PEG4-OH Structure

Tr-PEG4-OH

CAS#:125274-16-0

Literature: Breyholz, Hans-Joerg; Wagner, Stefan; Faust, Andreas; Riemann, Burkhard; Hoeltke, Carsten; Hermann, Sven; Schober, Otmar; Schaefers, Michael; Kopka, Klaus ChemMedChem, 2010 , vol. 5, # 5 p. 777 - 789

~70%

Tr-PEG4-OH Structure

Tr-PEG4-OH

CAS#:125274-16-0

Literature: Gartiser, Thierry; Selve, Claude; Mansuy, Laurence; Robert, Alain; Delpuech, Jean-Jacques Journal of Chemical Research, Miniprint, 1984 , # 9 p. 2672 - 2691

 Synonyms

2-(2-(2-(2-(trityloxy)ethoxy)ethoxy)ethoxy)ethanol
2,5,8,11-Tetraoxatridecan-13-ol,1,1,1-triphenyl
13,13,13-triphenyl-3,6,9,12-tetraoxatridecan-1-ol
Tr-PEG5
11-(triphenylmethyloxy)-3,6,9-trioxaundecan-1-ol
1,1,1-triphenyl-2,5,8,11-tetraoxatridecan-13-ol
13,13,13-triphenyl-3,6,9,12-tetraoxatridecanol
tetraethylene glycol monotrityl ether
TrtO-4eg-OH
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: Tr-PEG5
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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