DC Chemicals Limited
China
Product Name: THP-PEG9
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: THP-PEG10
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658858-65-2

658858-65-2 structure

658858-65-2 structure

Name: THP-PEG9
Chemical Name: THP-PEG8-OH
CAS Number: 658858-65-2
Molecular Formula: C₂₁H₄₂O₁₀
Molecular Weight: 454.55
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-12 17:37:43
Modify Date: 2024-01-08 11:32:24
THP-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	THP-PEG8-OH

Description	THP-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₂₁H₄₂O₁₀
Molecular Weight	454.55