3-(3,4-Dimethoxyphenyl)propionic acid

Modify Date: 2024-01-10 11:09:16

3-(3,4-Dimethoxyphenyl)propionic acid Structure
3-(3,4-Dimethoxyphenyl)propionic acid structure
Common Name 3-(3,4-Dimethoxyphenyl)propionic acid
CAS Number 2107-70-2 Molecular Weight 210.227
Density 1.2±0.1 g/cm3 Boiling Point 344.2±27.0 °C at 760 mmHg
Molecular Formula C11H14O4 Melting Point 96-97 °C(lit.)
MSDS Chinese USA Flash Point 132.0±17.2 °C

 Use of 3-(3,4-Dimethoxyphenyl)propionic acid


3-(3,4-Dimethoxyphenyl)propanoic acid is an orally active short-chain fatty acids (SCFAs). 3-(3,4-Dimethoxyphenyl)propanoic acid stimulates γ globin gene expression, erythropoiesis in vivo and is used for the β hemoglobinopathies and other anemias[1].

 Names

Name 3-(3,4-dimethoxyphenyl)propanoic acid
Synonym More Synonyms

 3-(3,4-Dimethoxyphenyl)propionic acid Biological Activity

Description 3-(3,4-Dimethoxyphenyl)propanoic acid is an orally active short-chain fatty acids (SCFAs). 3-(3,4-Dimethoxyphenyl)propanoic acid stimulates γ globin gene expression, erythropoiesis in vivo and is used for the β hemoglobinopathies and other anemias[1].
Related Catalog
In Vivo 3-(3,4-Dimethoxyphenyl)propanoic acid (50, 150 mg/kg of iv or 50, 150, 200 mg/kg of orally) achieves concentrations significantly higher than targeted plasma levels for several hours after single 50 to 150 mg/kg doses[1].
References

[1]. Pace BS, et al. Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo. lood. 2002 Dec 15;100(13):4640-8.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 344.2±27.0 °C at 760 mmHg
Melting Point 96-97 °C(lit.)
Molecular Formula C11H14O4
Molecular Weight 210.227
Flash Point 132.0±17.2 °C
Exact Mass 210.089203
PSA 55.76000
LogP 1.58
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.522
Storage condition -20°C Freezer

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2918990090

 Synthetic Route

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles2

More Articles
Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo.

Blood 100(13) , 4640-8, (2002)

Orally bioactive compounds that induce gamma globin gene expression at tolerable doses are needed for optimal treatment of the beta-hemoglobinopathies. Short-chain fatty acids (SCFAs) of 2 to 6 carbon...

Metal-cinnamic acids interactions. Part IV. Synthesis, study and antimicrobial activity of copper (II) complexes of 3, 4-dimethoxyhydrocinnamic acid. Zoroddu MA and Berardi E.

Transition Met. Chem. (London) 14(4) , 269-72, (1989)

 Synonyms

3,4-Dimethoxy-benzenepropanoic acid
3-(3,4-Dimethoxyphenyl)propionic Acid
3-(3,4-Dimethoxyphenyl)propanoic acid
Benzenepropanoic acid, 3,4-dimethoxy-
3,4-Dimethoxyhydrocinnamic Acid
MFCD00002774
Benzenepropanoic acid,3,4-dimethoxy
3,5-Dimethoxyphenylpropionic acid
3-3,4-Dimethoxyphenylpropionic Acid
3-(3',4'-dimethoxyphenyl)propanoic acid
3-(4',5'-dimethoxyphenyl)propionic acid
EINECS 218-288-3
Donepezil Impurity 34