3,4-Dihydroxyhydrocinnamic acid

Modify Date: 2024-01-01 19:26:28

3,4-Dihydroxyhydrocinnamic acid Structure
3,4-Dihydroxyhydrocinnamic acid structure
Common Name 3,4-Dihydroxyhydrocinnamic acid
CAS Number 1078-61-1 Molecular Weight 182.173
Density 1.4±0.1 g/cm3 Boiling Point 417.5±30.0 °C at 760 mmHg
Molecular Formula C9H10O4 Melting Point 136-139 °C(lit.)
MSDS Chinese USA Flash Point 220.4±21.1 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 3,4-Dihydroxyhydrocinnamic acid


Dihydrocaffeic acid is a phenolic acid found in Gynura bicolor, reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Antioxidant potential and anti-inflammatory activity[1].

 Names

Name 3-(3,4-dihydroxyphenyl)propanoic acid
Synonym More Synonyms

 3,4-Dihydroxyhydrocinnamic acid Biological Activity

Description Dihydrocaffeic acid is a phenolic acid found in Gynura bicolor, reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Antioxidant potential and anti-inflammatory activity[1].
Related Catalog
Target

p38 MAPK

References

[1]. Oliveira MM, et al. Dihydrocaffeic Acid Prevents UVB-Induced Oxidative Stress Leading to the Inhibition of Apoptosis and MMP-1 Expression via p38 Signaling Pathway. Oxid Med Cell Longev. 2019 Jan 17;2019:2419096.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 417.5±30.0 °C at 760 mmHg
Melting Point 136-139 °C(lit.)
Molecular Formula C9H10O4
Molecular Weight 182.173
Flash Point 220.4±21.1 °C
Exact Mass 182.057907
PSA 77.76000
LogP 0.50
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.620

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MW5143500
CHEMICAL NAME :
Hydrocinnamic acid, 3,4-dihydroxy-
CAS REGISTRY NUMBER :
1078-61-1
BEILSTEIN REFERENCE NO. :
2213449
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C9-H10-O4
MOLECULAR WEIGHT :
182.19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
150 mg/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11,523,1988

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS MW5143500

 Synthetic Route

 Articles54

More Articles
A metabolite profiling approach to identify biomarkers of flavonoid intake in humans.

J. Nucl. Med. 139 , 2309-14, (2009)

Flavonoids are phytochemicals that are widespread in the human diet. Despite limitations in their bioavailability, experimental and epidemiological data suggest health benefits of flavonoid consumptio...

Poly(N-vinylimidazole/ethylene glycol dimethacrylate) for the purification and isolation of phenolic acids.

Anal. Chim. Acta 885 , 199-206, (2015)

In this study we report the novel polymeric resin poly(N-vinyl imidazole/ethylene glycol dimethacrylate) for the purification and isolation of phenolic acids. The monomer to crosslinker ratio and the ...

Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.

Bioorg. Med. Chem. 17 , 5219-28, (2009)

In the light of known HDAC inhibitors, 33 carboxylic acid derivatives were tested to understand the structural requirements for HDAC inhibition activity. Several modifications were applied to develop ...

 Synonyms

Dihydrocaffeate
3,4-dihydroxy-hydrocinnamicaci
Hydrocaffeate
hydrocaffeic acid
3-propionic acid
3,4-Dihydroxy-benzenepropanoic acid
3,4-Dihydroxydihydrocinnamic acid
3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID
3,4-Dihydroxybenzenepropionate
3,4-Dihydroxybenzenepropionic acid
dihydrocaffeic acid
3,4-dihydroxyhydrocinnamic acid
3-(3,4-Dihydroxyphenyl)propanoic acid
3-(3,4-Dihydroxyphenyl)propionate
Benzenepropanoic acid, 3,4-dihydroxy-
3,4-DIHYDROCAFFEIC ACID
3,4-Dihydroxyhydrocinnamate
phloretic acid
EINECS 214-083-8
3-(3,4-Dihydroxyphenyl)propionic acid,Hydrocaffeic acid
Dihydrocafeate
MFCD00002776
Top Suppliers:I want be here




Get all suppliers and price by the below link:

3,4-Dihydroxyhydrocinnamic acid suppliers


Price: ¥198/5g

Reference only. check more 3,4-Dihydroxyhydrocinnamic acid price