DBCO-acid

Modify Date: 2024-01-03 12:42:51

DBCO-acid Structure
DBCO-acid structure
Common Name DBCO-acid
CAS Number 1353016-70-2 Molecular Weight 305.32700
Density N/A Boiling Point N/A
Molecular Formula C19H15NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-acid


DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and drug-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690)[1].

 Names

Name 4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoic acid
Synonym More Synonyms

 DBCO-acid Biological Activity

Description DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and drug-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690)[1].
Related Catalog
Target

Cleavable

References

[1]. Zimmerman ES, et al. Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system. Bioconjug Chem. 2014 Feb 19;25(2):351-61.

 Chemical & Physical Properties

Molecular Formula C19H15NO3
Molecular Weight 305.32700
Exact Mass 305.10500
PSA 57.61000
LogP 2.86280

 Synonyms

DBCO acid 1
Top Suppliers:I want be here
  • GL Biochem (Shanghai) Ltd.
  • China
  • Product Name: DBCO-acid
  • Price: ¥Inquiry/1kg ¥Inquiry/1g ¥Inquiry/1mg ¥Inquiry/1ton
  • Purity: 98.0%
  • Stocking Period: Inquiry
  • Contact: Jackie Yang

  • DC Chemicals Limited
  • China
  • Product Name: DBCO acid 1
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao



Get all suppliers and price by the below link:

DBCO-acid suppliers


Price: ¥500/10 mM * 1 mL in DMSO

Reference only. check more DBCO-acid price