1425485-72-8
1425485-72-8 structure
- Name: DBCO-C6-acid
- Chemical Name: 6-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-6-oxohexanoic acid
- CAS Number: 1425485-72-8
- Molecular Formula: C21H19NO3
- Molecular Weight: 333.380
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2018-06-28 12:29:50
- Modify Date: 2024-01-10 11:21:58
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DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues[1].
| Name | 6-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-6-oxohexanoic acid |
|---|---|
| Synonyms |
6-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-6-oxohexanoic acid
Dibenz[b,f]azocine-5(6H)-hexanoic acid, 11,12-didehydro-ε-oxo- DBCO acid 3 |
| Description | DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues[1]. |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 634.4±55.0 °C at 760 mmHg |
| Molecular Formula | C21H19NO3 |
| Molecular Weight | 333.380 |
| Flash Point | 337.5±31.5 °C |
| Exact Mass | 333.136505 |
| LogP | 4.48 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.654 |
| Hazard Codes | Xi |
|---|