2110448-99-0

2110448-99-0 structure

2110448-99-0 structure

Name: DBCO-PEG4-acid
Chemical Name: DBCO-PEG4-acid
CAS Number: 2110448-99-0
Molecular Formula: C₃₀H₃₆N₂O₈
Molecular Weight: 552.62
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2021-12-28 10:47:41
Modify Date: 2024-01-29 18:18:39
DBCO-PEG4-acid is a a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DBCO-PEG4-acid

Description	DBCO-PEG4-acid is a a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> PROTAC >> PROTAC Linker
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₃₀H₃₆N₂O₈
Molecular Weight	552.62