2-Hydroxy Atorvastatin-d5 disodium

Modify Date: 2024-01-21 21:20:49

2-Hydroxy Atorvastatin-d5 disodium Structure
2-Hydroxy Atorvastatin-d5 disodium structure
Common Name 2-Hydroxy Atorvastatin-d5 disodium
CAS Number 1276537-19-9 Molecular Weight 623.63400
Density N/A Boiling Point N/A
Molecular Formula C33H28D5FN2Na2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-Hydroxy Atorvastatin-d5 disodium


2-Hydroxy Atorvastatin-d5 (disodium) is the deuterium labeled 2-Hydroxy Atorvastatin disodium[1].

 Names

Name 2-Hydroxy Atorvastatin-d5 Disodium Salt
Synonym More Synonyms

 2-Hydroxy Atorvastatin-d5 disodium Biological Activity

Description 2-Hydroxy Atorvastatin-d5 (disodium) is the deuterium labeled 2-Hydroxy Atorvastatin disodium[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Molecular Formula C33H28D5FN2Na2O6
Molecular Weight 623.63400
Exact Mass 623.24300
PSA 141.17000
LogP 5.50670

 Synonyms

disodium,(3R,5R)-7-[2-(4-fluorophenyl)-4-[(2-oxidophenyl)carbamoyl]-3-(2,3,4,5,6-pentadeuteriophenyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate