265989-46-6

265989-46-6 structure

Name: 2-Hydroxy atorvastatin calcium salt
Chemical Name: calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
CAS Number: 265989-46-6
Molecular Formula: C₃₃H₃₄CaFN₂O₆
Molecular Weight: 613.70900
Catalog: Research Areas Metabolic Disease
Create Date: 2017-01-26 08:25:57
Modify Date: 2024-01-04 16:38:05
2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt. Atorvastatin is a potent HMG-CoA reductase inhibitor with an IC50 value of 8 nM.

Name	calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
Synonyms	2-Hydroxy atorvastatin calcium salt

Description	2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt. Atorvastatin is a potent HMG-CoA reductase inhibitor with an IC50 value of 8 nM.
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Borek-Dohalský V, et al. Validated HPLC-MS-MS method for simultaneous determination of atorvastatin and 2-hydroxyatorvastatin in human plasma-pharmacokinetic study. Anal Bioanal Chem. 2006 Sep;386(2):275-85.