2-Hydroxy atorvastatin calcium salt

Modify Date: 2024-01-04 16:38:05

2-Hydroxy atorvastatin calcium salt structure	Common Name	2-Hydroxy atorvastatin calcium salt
	CAS Number	265989-46-6	Molecular Weight	613.70900
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₃H₃₄CaFN₂O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2-Hydroxy atorvastatin calcium salt

2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt. Atorvastatin is a potent HMG-CoA reductase inhibitor with an IC50 value of 8 nM.

Name	calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
Synonym	More Synonyms

Description	2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt. Atorvastatin is a potent HMG-CoA reductase inhibitor with an IC50 value of 8 nM.
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Borek-Dohalský V, et al. Validated HPLC-MS-MS method for simultaneous determination of atorvastatin and 2-hydroxyatorvastatin in human plasma-pharmacokinetic study. Anal Bioanal Chem. 2006 Sep;386(2):275-85.

Molecular Formula	C₃₃H₃₄CaFN₂O₆
Molecular Weight	613.70900
Exact Mass	613.20300
PSA	138.34000
LogP	6.84140

2-Hydroxy atorvastatin calcium salt