1276537-19-9

1276537-19-9 structure

Name: 2-Hydroxy Atorvastatin-d5 disodium
Chemical Name: 2-Hydroxy Atorvastatin-d5 Disodium Salt
CAS Number: 1276537-19-9
Molecular Formula: C₃₃H₂₈D₅FN₂Na₂O₆
Molecular Weight: 623.63400
Catalog: Research Areas Others
Create Date: 2016-04-23 13:26:16
Modify Date: 2024-01-21 21:20:49
2-Hydroxy Atorvastatin-d5 (disodium) is the deuterium labeled 2-Hydroxy Atorvastatin disodium[1].

Name	2-Hydroxy Atorvastatin-d5 Disodium Salt
Synonyms	disodium,(3R,5R)-7-[2-(4-fluorophenyl)-4-[(2-oxidophenyl)carbamoyl]-3-(2,3,4,5,6-pentadeuteriophenyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate

Description	2-Hydroxy Atorvastatin-d5 (disodium) is the deuterium labeled 2-Hydroxy Atorvastatin disodium[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.