Br-PEG4-OH
Names
[ CAS No. ]:
85141-94-2
[ Name ]:
Br-PEG4-OH
[Synonym ]:
12-bromo-3,6,9,12-tetraoxadodecan-1-ol
2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]-ethanol
Biological Activity
[Description]:
Br-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Related Catalog]:
[Target]
PEGs
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C8H17BrO4
[ Molecular Weight ]:
257.12200
[ Exact Mass ]:
256.03100
[ PSA ]:
47.92000
[ LogP ]:
0.42340
Safety Information
[ Hazard Codes ]:
Xi