m-PEG4-Amine

Names

[ Name ]:
m-PEG4-Amine

[Synonym ]:
3,6,9,12-Tetraoxatridecan-1-amine
tetra(ethylene glycol) methyl ether amine
2,6-DIMETHYLANILINE,[3H]
1-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethylamine
2,5,8,11-tetraoxatridecan-13-amine
2-{2-[2-(2-methoxyethoxy)-ethoxy]-ethoxy}-ethylamine
EINECS 285-182-1
3,6,9,12-Tetraoxatridecylamine
methylethertetraethyleneglycol amine
2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethanamine

Biological Activity

[Description]:

m-PEG4-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1.

Chemical & Physical Properties

[ Density]:
1.005 g/cm3

[ Boiling Point ]:
276.701ºC at 760 mmHg

[ Molecular Formula ]:
C₉H₂₁NO₄

[ Molecular Weight ]:
207.26700

[ Exact Mass ]:
207.14700

[ PSA ]:
62.94000

[ LogP ]:
0.34160

[ Index of Refraction ]:
1.439

MSDS

Click to get detail MSDS

Safety Information

[ HS Code ]:
2921199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921199090

[ Summary ]:
2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%