PIM-IN-1

Names

[ CAS No. ]:
2698319-19-4

[ Name ]:
PIM-IN-1

Biological Activity

[Description]:

PIM-IN-1 is a pan-PIM kinase inhibitor (KG-1, EC50 = 61 nM; pS6, EC50 = 71 nM).

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> JAK/STAT Signaling >> Pim

[References]

[1]. Barberis C, et al. Discovery of SARxxxx92, a pan-PIM kinase inhibitor, efficacious in a KG1 tumor model. Bioorg Med Chem Lett. 2020 Dec 1;30(23):127625.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₈ClFN₄O

[ Molecular Weight ]:
324.78

Related Compounds

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