Pim-IN-22m

Names

[ Name ]:
Pim-IN-22m

Biological Activity

[Description]:

Pim-IN-22m is a potent, selective Pim1/Pim2 inhibitor with IC50 of 24/95 pM respectively; potently inhibits the phosphorylation of BAD (s112) in a cell line that expresses high levels of all Pim isoforms, KMS-12-BM (IC50=28 nM).

[References]

References 1. Wurz RP, et al. Bioorg Med Chem Lett. 2016 Nov 15;26(22):5580-5590. View Related Products by Target Pim

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₃F₂N₇

[ Molecular Weight ]:
435.483

Related Compounds

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