7-Epi-10-oxo-docetaxel

Names

[ Name ]:
7-Epi-10-oxo-docetaxel

[Synonym ]:
(2b,5b,7a,13a)-4-Acetoxy-13-(((2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl)oxy)-1,7-dihydroxy-9,10-dioxo-5,20-epoxytax-11-en-2-yl Benzoate
(2α,5β,7α,13α)-4-Acetoxy-1,7-dihydroxy-13-{[(2R,3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-9,10-dioxo-5,20-epoxytax-11-en-2-yl benzoate
7-Epi-10-oxo-docetaxel
Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4R,4aS,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-di hydroxy-4a,8,13,13-tetramethyl-5,6-dioxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
UNII-23YRN771SO

Biological Activity

[Description]:

7-Epi-10-oxo-docetaxel (Docetaxel Impurity D) is a impurity of docetaxel detected by high performance liquid chromatography (HPLC).

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin

Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin

Research Areas >> Cancer

[References]

[1]. Vasu Dev R, et al. Isolation and characterization of impurities in docetaxel. J Pharm Biomed Anal. 2006 Feb 24;40(3):614-22.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
887.3±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄₃H₅₁NO₁₄

[ Molecular Weight ]:
805.86300

[ Flash Point ]:
490.4±34.3 °C

[ Exact Mass ]:
805.33100

[ PSA ]:
224.78000

[ LogP ]:
6.29

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.614

[ Storage condition ]:
2-8℃

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.