Triflupromazine hydrochloride
Names
[ CAS No. ]:
1098-60-8
[ Name ]:
Triflupromazine hydrochloride
[Synonym ]:
Triflupromazine HCl
Fluorofen
N,N-Dimethyl-3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]-1-propanamine hydrochloride (1:1)
Nivoman
Trifluopromazine hydrochloride
N,N-dimethyl-3-[2-(trifluoromethyl)phenothiazin-10-yl]propan-1-amine,hydrochloride
flupromazine hydrochloride
N,N-Dimethyl-3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propan-1-amine hydrochloride (1:1)
10-[3-(Dimethylamino)propyl]-2-(trifluoromethyl)phenothiazine hydrochloride
N,N-dimethyl-3-[2-(trifluoromethyl)phenothiazin-10-yl]propan-1-amine hydrochloride
Phenothiazine, 10-(3-dimethylaminopropyl)-2-(trifluoromethyl)-, hydrochloride
Fluopromazinhydrochlorid
Vesprin hydrochloride
Neoprin
Flumazin
MFCD00058103
Phenothiazine, 10-[3- (dimethylamino)propyl]-2-(trifluoromethyl)-, monohydrochloride
Triflupromazine monohydrochloride
EINECS 214-149-6
Triflupromazine hydrochloride
10H-Phenothiazine-10-propanamine, N,N-dimethyl-2-(trifluoromethyl)-, hydrochloride (1:1)
triflupromazine
Biological Activity
[Description]:
[Related Catalog]:
[Related Small Molecules]
Chemical & Physical Properties
[ Boiling Point ]:
427.6ºC at 760 mmHg
[ Melting Point ]:
174.0 to 179.0 °C
[ Molecular Formula ]:
C18H20ClF3N2S
[ Molecular Weight ]:
388.878
[ Flash Point ]:
212.4ºC
[ Exact Mass ]:
388.098785
[ PSA ]:
31.78000
[ LogP ]:
6.12680
[ Vapour Pressure ]:
1.62E-07mmHg at 25°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SO8925000
- CHEMICAL NAME :
- Phenothiazine, 10-(3-(dimethylamino)propyl)-2-(trifluoromethyl)-, monohydrochloride
- CAS REGISTRY NUMBER :
- 1098-60-8
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C18-H19-F3-N2-S.Cl-H
- MOLECULAR WEIGHT :
- 388.91
- WISWESSER LINE NOTATION :
- T C666 BN ISJ B3N1&1 EXFFF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 94 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 254 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 102 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 34 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 17 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - respiratory obstruction Blood - hemorrhage
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Mammal - species unspecified Kidney
- DOSE/DURATION :
- 10 mg/L
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 8,617,1970
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H312 + H332
[ Precautionary Statements ]:
Missing Phrase - N15.00950417-P261-P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R20/21/22
[ Safety Phrases ]:
36
[ RIDADR ]:
UN 2811 6
[ WGK Germany ]:
3
[ RTECS ]:
SO8925000
[ Packaging Group ]:
III