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Enterocin

Enterocin用途

肠霉素是一种抗生素,对革兰氏阳性和革兰氏阴性细菌具有静态活性,对真菌和酵母没有活性[1]。

Enterocin名称

[ CAS 号 ]:
59678-46-5

[ 中文名 ]:
肠球蛋白

[ 英文名 ]:
Enterocin

[英文别名 ]:

Enterocin,vulgamycin
Vulgamycin

Enterocin生物活性

[ 描述 ]:

肠霉素是一种抗生素,对革兰氏阳性和革兰氏阴性细菌具有静态活性,对真菌和酵母没有活性[1]。

[ 相关类别 ]:

研究领域 >> 炎症/免疫

信号通路 >> 抗感染 >> 细菌

[参考文献]

[1]. N Miyairi, et al, Enterocin, a new antibiotic taxonomy, isolation and characterization. J Antibiot (Tokyo). 1976 Mar;29(3):227-35.

Enterocin物理化学性质

[ 密度 ]:
1.67 g/cm3

[ 沸点 ]:
726.3ºC at 760 mmHg

[ 分子式 ]:
C₂₂H₂₀O₁₀

[ 分子量 ]:
444.38800

[ 闪点 ]:
257.4ºC

[ 精确质量 ]:
444.10600

[ PSA ]:
163.73000

[ 折射率 ]:
1.712

[ 储存条件 ]:
-20°C，密闭，干燥

Enterocin毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: PB9245500

CHEMICAL NAME :: 3,6-Methanocylopenta(c)pyran-1(3H)-one, hexahydro-7-benzoyl-5-(4-methoxy-2-oxo-2H-pyran-6- yl)-4a,6,7a,8-tetrahydroxy-, (3R-(3-alpha,4a-beta,5-alpha,6-beta,7-beta,7a-beta,8R *))-

CAS REGISTRY NUMBER :: 59678-46-5

LAST UPDATED :: 199212

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C22-H20-O10

MOLECULAR WEIGHT :: 444.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 29,227,1976

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 29,227,1976