盐酸环己胺
盐酸环己胺用途
有机合成。
盐酸环己胺名称
[ CAS 号 ]:
4998-76-9
[ 中文名 ]:
盐酸环己胺
[ 英文名 ]:
Cyclohexanamine hydrochloride (1:1)
[中文别名 ]:
[英文别名 ]:
- Benzenamine, 3,5-dihydro-, hydrochloride
- cyclohexanamine,hydrochloride
- Cyclohexanamine hydrochloride (1:1)
- MFCD00050540
- EINECS 225-661-4
- Cyclohexanamine, hydrochloride (1:1)
- Cyclohexanamine hydrochloride
- CyclohexylaMine Hydrochloride
- Glipizide Impurity 2
盐酸环己胺物理化学性质
[ 密度 ]:
4.7 (Vapor Density)
[ 沸点 ]:
306 °C
[ 熔点 ]:
207 °C
[ 分子式 ]:
C6H14ClN
[ 分子量 ]:
135.635
[ 闪点 ]:
32.2ºC
[ 精确质量 ]:
135.081482
[ PSA ]:
26.02000
[ LogP ]:
2.78010
[ 外观性状 ]:
白色固体
[ 储存条件 ]:
存放于惰性气体之中;避免湿气 (吸湿)
[ 水溶解性 ]:
83 g/100 mL (17 ºC)
盐酸环己胺MSDS
盐酸环己胺毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GX1440000
- CHEMICAL NAME :
- Cyclohexylamine, hydrochloride
- CAS REGISTRY NUMBER :
- 4998-76-9
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 19
- MOLECULAR FORMULA :
- C6-H13-N.Cl-H
- MOLECULAR WEIGHT :
- 135.66
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 720 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Behavioral - muscle contraction or spasticity Behavioral - coma
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 350 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - changes in structure or function of salivary glands Skin and Appendages - hair
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 760 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Behavioral - muscle contraction or spasticity Behavioral - coma
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Gastrointestinal - changes in structure or function of salivary glands Lungs, Thorax, or Respiration - other changes
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Cardiac - pulse rate increase, without fall in BP
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 520 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Behavioral - muscle contraction or spasticity Behavioral - coma
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 432 mg/kg/30D-I
- TOXIC EFFECTS :
- Blood - normocytic anemia Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 219 gm/kg/2Y-C
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9100 mg/kg/13W-C
- TOXIC EFFECTS :
- Behavioral - fluid intake Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - changes in ovarian weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 45 gm/kg/13W-C
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - changes in testicular weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 32400 mg/kg
- SEX/DURATION :
- male 90 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- Sperm Morphology
MUTATION DATA
- TEST SYSTEM :
- Rodent - hamster
- DOSE/DURATION :
- 600 mg/kg/3D (Continuous)
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 13,415,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5404 No. of Facilities: 4290 (estimated) No. of Industries: 48 No. of Occupations: 43 No. of Employees: 53611 (estimated) No. of Female Employees: 16742 (estimated)
盐酸环己胺安全信息
[ 危害码 (欧洲) ]:
Xn:Harmful;
[ 风险声明 (欧洲) ]:
R20/21/22;R36/37/38
[ 安全声明 (欧洲) ]:
S36/37/39-S26
[ RTECS号 ]:
GX1440000
[ 海关编码 ]:
2921300090
盐酸环己胺合成路线
盐酸环己胺上下游产品
盐酸环己胺上游产品
盐酸环己胺下游产品
盐酸环己胺海关
[ 海关编码 ]: 2921300090
[ 中文概述 ]:
2921300090 其他环(烷,烯,萜烯)单胺或多胺(包括其衍生物及它们的盐). 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
相关化工产品/化学物质:
推荐生产厂家/供应商:
公司名:南通润丰石油化工有限公司
区域:南通市崇川区
价格:
¥需询单/1kg
¥需询单/1ton
联系人:曹经理
产品详情:盐酸环己胺
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥228.0/500g
¥78.0/100g
联系人:刘佳
产品详情:环己胺盐酸盐
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥49.9/100g
¥98.9/250g
¥36.9/25g
¥175.9/500g
联系人:阿拉丁李高志
产品详情:环己胺盐酸盐
公司名:上海创赛科技有限公司
区域:上海市嘉定区
价格:
¥55.0/100g
¥184.0/500g
¥741.0/2500g
联系人:夏言
公司名:中山市迪欣化工有限公司
区域:中山市三角镇
价格:
¥58.0/50kg
联系人:王洁
产品详情:环己胺盐酸盐
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相关化合物
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