硫双乙醇

硫双乙醇用途

【用途一】
本品用作酞菁素IF3G各种阳离子染料、还原染料的助溶助。也可用作还原染料印花用调浆剂、匀染剂、吸温剂。做染料助溶剂能增加得色量和鲜艳度。
【用途二】
印染用染料溶剂，例如酸性染料、碱性染料等；油墨溶剂；农药原料；照相显影剂的增敏剂；缓蚀剂；润滑油添加剂；纤维防缩剂；聚烯烃稳定剂。

硫双乙醇名称

[ CAS 号 ]:
111-48-8

[ 中文名 ]:
硫二甘醇

[ 英文名 ]:
thiodiglycol

[中文别名 ]:

[英文别名 ]:

Ethanol, 2,2'-thiobis-
2,2-DIMETHYL-CHROMAN-6-SULFONYL CHLORIDE
2,2'-Sulfanediyldiethanol
2,2-Thiodiethanol
MFCD00002910
THIODIETHANOL
2-[(2-HYDROXYETHYL)THIO]ETHANOL
EINECS 203-874-3
2,2'-Thiodiethanol
2 2'-THIODIETHANOL

硫双乙醇物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
282.0±0.0 °C at 760 mmHg

[ 熔点 ]:
−16 °C(lit.)

[ 分子式 ]:
C₄H₁₀O₂S

[ 分子量 ]:
122.186

[ 闪点 ]:
139.5±19.1 °C

[ 精确质量 ]:
122.040154

[ PSA ]:
65.76000

[ LogP ]:
-0.71

[ 外观性状 ]:
透明无色至略黄色液体

[ 蒸汽压 ]:
0.0±1.3 mmHg at 25°C

[ 折射率 ]:
1.523

[ 储存条件 ]:
?20°C

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents. Reacts with a wide variety of compounds. Flammable.

硫双乙醇MSDS

硫双乙醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KM2975000

CHEMICAL NAME :: Ethanol, 2,2'-thiodi-

CAS REGISTRY NUMBER :: 111-48-8

BEILSTEIN REFERENCE NO. :: 1236325

LAST UPDATED :: 199701

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C4-H10-O2-S

MOLECULAR WEIGHT :: 122.20

WISWESSER LINE NOTATION :: Q2S2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/3/1971

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6610 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 23,259,1941

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,1,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Gastrointestinal - other changes Liver - hepatitis (hepatocellular necrosis), diffuse Endocrine - other changes

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,1,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 20 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/3/1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,1,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 3960 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 23,259,1941 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82023 No. of Facilities: 167 (estimated) No. of Industries: 6 No. of Occupations: 13 No. of Employees: 5259 (estimated)

硫双乙醇安全信息

[ 符号 ]:

GHS02, GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H301 + H311 + H331-H370

[ 警示性声明 ]:
P210-P260-P280-P301 + P310-P311

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36

[ 安全声明 (欧洲) ]:
S23-S26-S36/37/39-S45-S36

[ 危险品运输编码 ]:
UN3334 9

[ WGK德国 ]:
1

[ RTECS号 ]:
KM2975000

[ 海关编码 ]:
2930909026

硫双乙醇合成路线

硫双乙醇上下游产品

硫双乙醇上游产品

硫双乙醇下游产品

硫双乙醇制备

将氯乙醇、硫化钠依次加入反应釜中，边搅拌边升温至90～95℃。反应完毕后，将物料冷却，再用硫酸中和至ｐＨ值呈中性。经过滤、减压蒸馏收集硫代双乙醇馏分。

硫双乙醇海关

[ 海关编码 ]: 2930909026

[ 中文概述 ]:
2930909026 硫二甘醇〔二(3-羟乙基)硫醚、硫代双乙醇〕。监管条件:23(两用物项和技术进口许可证,两用物项和技术出口许可证)。增值税率:17.0%。退税率:9.0%。最低关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: 2.两用物项和技术进口许可证 3.两用物项和技术出口许可证

[ Summary ]:
2930909026 2,2'-thiodiethanol。supervision conditions:23(import license for dual-use item and technologies,export license for dual-use item and technologies)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

硫双乙醇文献

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

J. Med. Chem. 51 , 6740-51, (2008)

The work provides a new model for the prediction of the MAO-A and -B inhibitor activity by the use of combined complex networks and QSAR methodologies. On the basis of the obtained model, we prepared ...

Redox Regulation of Cell Contacts by Tricellulin and Occludin: Redox-Sensitive Cysteine Sites in Tricellulin Regulate Both Tri- and Bicellular Junctions in Tissue Barriers as Shown in Hypoxia and Ischemia.

Antioxid. Redox Signal. 23 , 1035-49, (2015)

Tight junctions (TJs) seal paracellular clefts in epithelia/endothelia and form tissue barriers for proper organ function. TJ-associated marvel proteins (TAMPs; tricellulin, occludin, marvelD3) are th...

Developmental toxicity of thiodiglycol in Sprague-Dawley rats.

Int. J. Toxicol. 26(4) , 365-71, (2007)

Thiodiglycol (TG), a hydrolysis product of sulfur mustard (HD), is a potential contaminant of soil and water at certain military sites. To establish developmental toxicity criteria for TG, an oral dev...

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