FK-866 Hydrochloride

• 常用名: FK-866 Hydrochloride
• 英文名: FK-866 Hydrochloride
• CAS号: 1785666-54-7
• 分子量: 427.967
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₃₀ClN₃O₂
• 熔点: N/A
• 闪点: N/A

FK-866 Hydrochloride用途

Daporinad, also known as APO-866 and FK866, is a small molecule with potential antineoplastic and antiangiogenic activities. NMPRTase inhibitor APO866 binds to and inhibits nicotinamide phosphoribosyltransferase (NMPRTase), inhibiting the biosynthesis of nicotinamide adenine dinucleotide (NAD+) from niacinamide (vitamin B3), which may deplete energy reserves in metabolically active tumor cells and induce tumor cell apoptosis. In addition, this agent may inhibit tumor cell prioduction of vascular endothelial growth factor (VEGF), resulting in the inhibition of tumor angiogenesis.

FK-866 Hydrochloride名称

• 英文名: (2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)acrylamide hydrochloride (1:1)

FK-866 Hydrochloride物理化学性质

• 分子式: C₂₄H₃₀ClN₃O₂
• 分子量: 427.967
• 精确质量: 427.202667

FK-866 Hydrochloride英文别名

• (2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)acrylamide hydrochloride (1:1)
• 2-Propenamide, N-[4-(1-benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-, (2E)-, hydrochloride (1:1)
• MFCD10565943