1,1-Dioxothiolan-d8

Modify Date: 2024-01-13 12:44:50

1,1-Dioxothiolan-d8 Structure
1,1-Dioxothiolan-d8 structure
Common Name 1,1-Dioxothiolan-d8
CAS Number 51219-88-6 Molecular Weight 128.21900
Density N/A Boiling Point 283-285ºC
Molecular Formula C4D8O2S Melting Point 25-27ºC
MSDS Chinese USA Flash Point 177ºC

 Use of 1,1-Dioxothiolan-d8


1,1-Dioxothiolan-d8 is the deuterium labeled 1,1-Dioxothiolan[1].

 Names

Name tetramethylene-d8 sulfone
Synonym More Synonyms

 1,1-Dioxothiolan-d8 Biological Activity

Description 1,1-Dioxothiolan-d8 is the deuterium labeled 1,1-Dioxothiolan[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Boiling Point 283-285ºC
Melting Point 25-27ºC
Molecular Formula C4D8O2S
Molecular Weight 128.21900
Flash Point 177ºC
Exact Mass 128.07500
PSA 42.52000
LogP 1.27580

 Safety Information

Hazard Codes Xn
Risk Phrases R22
Safety Phrases S25

 Synonyms

Sulfolane-d8
MFCD00148960