DW-1350

Modify Date: 2024-01-10 19:27:23

DW-1350 Structure
DW-1350 structure
Common Name DW-1350
CAS Number 491577-61-8 Molecular Weight 453.59700
Density N/A Boiling Point N/A
Molecular Formula C25H31N3O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DW-1350


DW-1350 is a LTB4 receptor antagonist.

 Names

Name N'-hydroxy-4-[5-[4-(2-methyl-5-propan-2-yl-1,3-thiazol-4-yl)phenoxy]pentoxy]benzenecarboximidamide
Synonym More Synonyms

 DW-1350 Biological Activity

Description DW-1350 is a LTB4 receptor antagonist.
Related Catalog
Target

LTB4

In Vitro DW-1350 is a LTB4 receptor antagonist. DW-1350 shows inhibitory effects against osteoclast in terms of differentiation, formation, fusion and bone absorption[1].
References

[1]. Kang JH, et al. 5-Lipoxygenase inhibitors suppress RANKL-induced osteoclast formation via NFATc1expression. Bioorg Med Chem. 2015 Nov 1;23(21):7069-78.

 Chemical & Physical Properties

Molecular Formula C25H31N3O3S
Molecular Weight 453.59700
Exact Mass 453.20900
PSA 118.20000
LogP 6.66480
Storage condition 2-8℃

 Synonyms

dw-1350
unii-1cd2z2ggyn