491577-61-8

491577-61-8 structure

Name: DW-1350
Chemical Name: N'-hydroxy-4-[5-[4-(2-methyl-5-propan-2-yl-1,3-thiazol-4-yl)phenoxy]pentoxy]benzenecarboximidamide
CAS Number: 491577-61-8
Molecular Formula: C₂₅H₃₁N₃O₃S
Molecular Weight: 453.59700
Catalog: Signaling Pathways GPCR/G Protein Leukotriene Receptor
Create Date: 2016-12-02 11:19:58
Modify Date: 2024-01-10 19:27:23
DW-1350 is a LTB4 receptor antagonist.

Name	N'-hydroxy-4-[5-[4-(2-methyl-5-propan-2-yl-1,3-thiazol-4-yl)phenoxy]pentoxy]benzenecarboximidamide
Synonyms	dw-1350 unii-1cd2z2ggyn

Description	DW-1350 is a LTB4 receptor antagonist.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Leukotriene Receptor Research Areas >> Inflammation/Immunology
Target	LTB4
In Vitro	DW-1350 is a LTB4 receptor antagonist. DW-1350 shows inhibitory effects against osteoclast in terms of differentiation, formation, fusion and bone absorption[1].
References	[1]. Kang JH, et al. 5-Lipoxygenase inhibitors suppress RANKL-induced osteoclast formation via NFATc1expression. Bioorg Med Chem. 2015 Nov 1;23(21):7069-78.