DW-1350

Names

[ CAS No. ]:
491577-61-8

[ Name ]:
DW-1350

[Synonym ]:
dw-1350
unii-1cd2z2ggyn

Biological Activity

[Description]:

DW-1350 is a LTB4 receptor antagonist.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Leukotriene Receptor
Research Areas >> Inflammation/Immunology

[Target]

LTB4


[In Vitro]

DW-1350 is a LTB4 receptor antagonist. DW-1350 shows inhibitory effects against osteoclast in terms of differentiation, formation, fusion and bone absorption[1].

[References]

[1]. Kang JH, et al. 5-Lipoxygenase inhibitors suppress RANKL-induced osteoclast formation via NFATc1expression. Bioorg Med Chem. 2015 Nov 1;23(21):7069-78.


[Related Small Molecules]

MK-571 | Zafirlukast | Pranlukast | Nedocromil | AS-35 | LY223982 | Darbufelone mesilate | LM-1484 | Quinotolast sodium | RG-12525 | RS-601 | Tipelukast | CI-949 | CP 105696 | CP-96486

Chemical & Physical Properties

[ Molecular Formula ]:
C25H31N3O3S

[ Molecular Weight ]:
453.59700

[ Exact Mass ]:
453.20900

[ PSA ]:
118.20000

[ LogP ]:
6.66480

[ Storage condition ]:
2-8℃

Related Compounds