8-azidoadenosine

Modify Date: 2024-01-11 14:14:09

8-azidoadenosine Structure
8-azidoadenosine structure
Common Name 8-azidoadenosine
CAS Number 4372-67-2 Molecular Weight 308.25
Density N/A Boiling Point N/A
Molecular Formula C10H12N8O4 Melting Point >200ºC (dec.)
MSDS N/A Flash Point N/A

 Use of 8-azidoadenosine


8-Azidoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

 Names

Name 8-Azido Adenosine
Synonym More Synonyms

 8-azidoadenosine Biological Activity

Description 8-Azidoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

 Chemical & Physical Properties

Melting Point >200ºC (dec.)
Molecular Formula C10H12N8O4
Molecular Weight 308.25
Exact Mass 308.09800
PSA 189.29000
Storage condition Amber Vial, Refrigerator, Under Inert Atmosphere

 Synthetic Route

~75%

8-azidoadenosine Structure

8-azidoadenosine

CAS#:4372-67-2

Literature: Sayed Ahmed Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1996 , vol. 35, # 6 p. 595 - 597

~57%

8-azidoadenosine Structure

8-azidoadenosine

CAS#:4372-67-2

Literature: Frieden, Miriam; Avino, Anna; Eritja, Ramon Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 2 p. 193 - 202

 Synonyms

8-azidoadenosine