NE21650

Modify Date: 2024-01-06 19:14:18

NE21650 Structure
NE21650 structure
Common Name NE21650
CAS Number 427899-21-6 Molecular Weight 297.14
Density N/A Boiling Point N/A
Molecular Formula C8H13NO7P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NE21650


NE21650 potently inhibits farnesyl diphosphate (FPP) synthase. NE21650 is a weak inhibitor of isopentenyl diphosphate (IPP) isomerase. NE21650 is a potent inhibitor of protein prenylation in osteoclasts and macrophages and bone resorption in vitro[1].

 Names

Name NE21650
Synonym More Synonyms

 NE21650 Biological Activity

Description NE21650 potently inhibits farnesyl diphosphate (FPP) synthase. NE21650 is a weak inhibitor of isopentenyl diphosphate (IPP) isomerase. NE21650 is a potent inhibitor of protein prenylation in osteoclasts and macrophages and bone resorption in vitro[1].
Related Catalog
References

[1]. Keith Thompson, et al. Identification of a bisphosphonate that inhibits isopentenyl diphosphate isomerase and farnesyl diphosphate synthase. Biochem Biophys Res Commun. 2002 Jan 18;290(2):869-73.  

 Chemical & Physical Properties

Molecular Formula C8H13NO7P2
Molecular Weight 297.14

 Synonyms

NE 21650
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