NE21650

Names

[ Name ]:
NE21650

[Synonym ]:
NE 21650

Biological Activity

[Description]:

NE21650 potently inhibits farnesyl diphosphate (FPP) synthase. NE21650 is a weak inhibitor of isopentenyl diphosphate (IPP) isomerase. NE21650 is a potent inhibitor of protein prenylation in osteoclasts and macrophages and bone resorption in vitro[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Keith Thompson, et al. Identification of a bisphosphonate that inhibits isopentenyl diphosphate isomerase and farnesyl diphosphate synthase. Biochem Biophys Res Commun. 2002 Jan 18;290(2):869-73.

Chemical & Physical Properties

[ Molecular Formula ]:
C₈H₁₃NO₇P₂

[ Molecular Weight ]:
297.14

Related Compounds

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