427899-21-6

427899-21-6 structure

Name: NE21650
Chemical Name: NE21650
CAS Number: 427899-21-6
Molecular Formula: C₈H₁₃NO₇P₂
Molecular Weight: 297.14
Catalog: Research Areas Metabolic Disease
Create Date: 2023-10-30 16:12:46
Modify Date: 2024-01-06 19:14:18
NE21650 potently inhibits farnesyl diphosphate (FPP) synthase. NE21650 is a weak inhibitor of isopentenyl diphosphate (IPP) isomerase. NE21650 is a potent inhibitor of protein prenylation in osteoclasts and macrophages and bone resorption in vitro[1].

Name	NE21650
Synonyms	NE 21650

Description	NE21650 potently inhibits farnesyl diphosphate (FPP) synthase. NE21650 is a weak inhibitor of isopentenyl diphosphate (IPP) isomerase. NE21650 is a potent inhibitor of protein prenylation in osteoclasts and macrophages and bone resorption in vitro[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Keith Thompson, et al. Identification of a bisphosphonate that inhibits isopentenyl diphosphate isomerase and farnesyl diphosphate synthase. Biochem Biophys Res Commun. 2002 Jan 18;290(2):869-73.

Molecular Formula	C₈H₁₃NO₇P₂
Molecular Weight	297.14