ROS kinases-IN-1

Modify Date: 2024-04-04 00:01:01

ROS kinases-IN-1 structure	Common Name	ROS kinases-IN-1
	CAS Number	370096-57-4	Molecular Weight	328.373
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₆N₄O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ROS kinases-IN-1

ROS kinases-IN-1 (pag 98) is a ROS tyrosine kinase inhibitor with IC50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity[1].

Name	WAY-602746

Description	ROS kinases-IN-1 (pag 98) is a ROS tyrosine kinase inhibitor with IC50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS
Target	IC50: 1.22 μM (ROS kinase)[1]
In Vitro	ROS kinases-IN-1 (1-100 μM; 1 d) inhibits the growth of cervical cancer cell and glioblastoma cells[1]. Cell Viability Assay[1] Cell Line: HeLa, U138, U87, LN18, and U118 cells Concentration: 1, 10, and 100 μM Incubation Time: one day Result: Showed EC50s for HeLa, U138, U87, LN18, and U118 cells of 20, 8, 8, 12, and 7 μM, respectively.
References	[1]. Dorre A. GRUENEBERG, et al. Novel methods, compounds, and compositions for inhibition of ros. WO2014141129A2.

Molecular Formula	C₂₀H₁₆N₄O
Molecular Weight	328.373