D-KLVFFA
Modify Date: 2024-01-12 12:55:25
D-KLVFFA structure
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Common Name | D-KLVFFA | ||
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| CAS Number | 342877-55-8 | Molecular Weight | 837.92500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C40H58F3N7O9 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of D-KLVFFAD-KLVFFA is the inhibitor of Amyloid-β assembly, with the IC50 of 2.6 μM, that can be used in Alzheimer's disease study[1]. |
| Name | (2R)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2,6-diaminohexanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]propanoic acid,2,2,2-trifluoroacetic acid |
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| Synonym | More Synonyms |
| Description | D-KLVFFA is the inhibitor of Amyloid-β assembly, with the IC50 of 2.6 μM, that can be used in Alzheimer's disease study[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C40H58F3N7O9 |
|---|---|
| Molecular Weight | 837.92500 |
| Exact Mass | 837.42500 |
| PSA | 289.59000 |
| LogP | 7.39410 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
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Stereoselective interactions of peptide inhibitors with the beta-amyloid peptide.
J. Biol. Chem. 278 , 34874-34881, (2003) Residues 16-20 of the beta-amyloid peptide (A beta) function as a self-recognition element during A beta assembly into fibers. Peptides containing this motif retain the ability to interact with A beta... |
| D-Lys-D-Leu-D-Val-D-Phe-D-Phe-D-Ala trifluoroacetate salt |
| D-KLVFFA |