Anticancer agent 128
Modify Date: 2024-01-29 18:52:53
Anticancer agent 128 structure
|
Common Name | Anticancer agent 128 | ||
|---|---|---|---|---|
| CAS Number | 2941243-62-3 | Molecular Weight | 470.60 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H38N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Anticancer agent 128Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently targets the BIR3 domains of XIAP, cIAP1, and cIAP2. Anticancer agent 128 targets the BIR3 domains of XIAP, cIAP1, and cIAP2 with IC50s of 24.9 nM, 19.3 nM, and 10.3 nM, respectively[1]. |
| Name | Anticancer agent 128 |
|---|
| Description | Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently targets the BIR3 domains of XIAP, cIAP1, and cIAP2. Anticancer agent 128 targets the BIR3 domains of XIAP, cIAP1, and cIAP2 with IC50s of 24.9 nM, 19.3 nM, and 10.3 nM, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 27.2 nM (XIAP-BIR3), 16.6 nM (cIAP1-BIR3), and 8.4 nM (cIAP2-BIR3)[1] |
| References |
| Molecular Formula | C26H38N4O4 |
|---|---|
| Molecular Weight | 470.60 |