2941243-62-3
2941243-62-3 structure
- Name: Anticancer agent 128
- Chemical Name: Anticancer agent 128
- CAS Number: 2941243-62-3
- Molecular Formula: C26H38N4O4
- Molecular Weight: 470.60
- Catalog: Signaling Pathways Apoptosis IAP
- Create Date: 2023-10-07 18:24:43
- Modify Date: 2024-01-29 18:52:53
-
Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently targets the BIR3 domains of XIAP, cIAP1, and cIAP2. Anticancer agent 128 targets the BIR3 domains of XIAP, cIAP1, and cIAP2 with IC50s of 24.9 nM, 19.3 nM, and 10.3 nM, respectively[1].
| Name | Anticancer agent 128 |
|---|
| Description | Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently targets the BIR3 domains of XIAP, cIAP1, and cIAP2. Anticancer agent 128 targets the BIR3 domains of XIAP, cIAP1, and cIAP2 with IC50s of 24.9 nM, 19.3 nM, and 10.3 nM, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 27.2 nM (XIAP-BIR3), 16.6 nM (cIAP1-BIR3), and 8.4 nM (cIAP2-BIR3)[1] |
| References |
| Molecular Formula | C26H38N4O4 |
|---|---|
| Molecular Weight | 470.60 |