Antitumor agent-38
Modify Date: 2025-08-25 18:00:46
Antitumor agent-38 structure
|
Common Name | Antitumor agent-38 | ||
|---|---|---|---|---|
| CAS Number | 2744193-34-6 | Molecular Weight | 380.44 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H24N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Antitumor agent-38Antitumor agent-38 is a potent antitumor agents. Antitumor agent-38 shows antiproliferative activity for cancer cells. Antitumor agent-38 induces cell cycle arrest at the late S and G2/M phase without interfering with microtubule formation or cell morphology[1]. |
| Name | Antitumor agent-38 |
|---|
| Description | Antitumor agent-38 is a potent antitumor agents. Antitumor agent-38 shows antiproliferative activity for cancer cells. Antitumor agent-38 induces cell cycle arrest at the late S and G2/M phase without interfering with microtubule formation or cell morphology[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Antitumor agent-38 (compound 9h) shows antiproliferative activity with GI50s of 0.66, 0.85, 0.76, 4.12, 3.67 µM for A549, MDA-MB-231, KB, KB-VIN, MCF-7 cells, respectively[1]. Antitumor agent-38 (0.58, 1.74 µM; 24 h) induces cell cycle arrest at the late S and G2/M phase[1]. Cell Cycle Analysis[1] Cell Line: MDA-MB-231 cells Concentration: 0.85, 1.74 µM Incubation Time: 24 h Result: Cells were arrested at the late S and G2/M phase. |
| References |
| Molecular Formula | C22H24N2O4 |
|---|---|
| Molecular Weight | 380.44 |
| InChIKey | VLINPCHNMXCDLY-UHFFFAOYSA-N |
| SMILES | COc1cc2c(cc1O)c(CN1CCC(N)CC1)cc1cc3c(cc12)OCO3 |