2744193-34-6

2744193-34-6 structure

Name: Antitumor agent-38
Chemical Name: Antitumor agent-38
CAS Number: 2744193-34-6
Molecular Formula: C₂₂H₂₄N₂O₄
Molecular Weight: 380.44
Catalog: Research Areas Cancer
Create Date: 2022-07-12 01:58:15
Modify Date: 2025-08-25 18:00:46
Antitumor agent-38 is a potent antitumor agents. Antitumor agent-38 shows antiproliferative activity for cancer cells. Antitumor agent-38 induces cell cycle arrest at the late S and G2/M phase without interfering with microtubule formation or cell morphology[1].

Name	Antitumor agent-38

Description	Antitumor agent-38 is a potent antitumor agents. Antitumor agent-38 shows antiproliferative activity for cancer cells. Antitumor agent-38 induces cell cycle arrest at the late S and G2/M phase without interfering with microtubule formation or cell morphology[1].
Related Catalog	Research Areas >> Cancer
In Vitro	Antitumor agent-38 (compound 9h) shows antiproliferative activity with GI50s of 0.66, 0.85, 0.76, 4.12, 3.67 µM for A549, MDA-MB-231, KB, KB-VIN, MCF-7 cells, respectively[1]. Antitumor agent-38 (0.58, 1.74 µM; 24 h) induces cell cycle arrest at the late S and G2/M phase[1]. Cell Cycle Analysis[1] Cell Line: MDA-MB-231 cells Concentration: 0.85, 1.74 µM Incubation Time: 24 h Result: Cells were arrested at the late S and G2/M phase.
References	[1]. Xie L,et al. Lead Optimization: Synthesis and Biological Evaluation of PBT-1 Derivatives as Novel Antitumor Agents. ACS Med Chem Lett. 2021; 12(12):1948-1954.

Molecular Formula	C₂₂H₂₄N₂O₄
Molecular Weight	380.44