PI3Kγ inhibitor 7

Modify Date: 2024-01-22 06:03:03

PI3Kγ inhibitor 7 Structure
PI3Kγ inhibitor 7 structure
Common Name PI3Kγ inhibitor 7
CAS Number 2575863-25-9 Molecular Weight 555.59
Density N/A Boiling Point N/A
Molecular Formula C31H25N9O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PI3Kγ inhibitor 7


PI3Kγ inhibitor 7 (compound 2) is a potent and orally active PI3Kγ inhibitor with IC50 values of 4768, 878.1, 3.42, 355.2 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, respectively. PI3Kγ inhibitor 7 shows antitumor activity[1].

 Names

Name PI3Kγ inhibitor 7

 PI3Kγ inhibitor 7 Biological Activity

Description PI3Kγ inhibitor 7 (compound 2) is a potent and orally active PI3Kγ inhibitor with IC50 values of 4768, 878.1, 3.42, 355.2 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, respectively. PI3Kγ inhibitor 7 shows antitumor activity[1].
Related Catalog
Target

PI3Kα:4768 nM (IC50)

PI3Kβ:878.1 nM (IC50)

PI3Kγ:3.42 nM (IC50)

PI3Kδ:355.2 nM (IC50)

References

[1]. HeJun Lv, et al. Alkyne derivative, preparation method for same, and uses thereof. WO2021004421A1.

 Chemical & Physical Properties

Molecular Formula C31H25N9O2
Molecular Weight 555.59
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