2575863-25-9

2575863-25-9 structure
2575863-25-9 structure
  • Name: PI3Kγ inhibitor 7
  • Chemical Name: PI3Kγ inhibitor 7
  • CAS Number: 2575863-25-9
  • Molecular Formula: C31H25N9O2
  • Molecular Weight: 555.59
  • Catalog: Signaling Pathways PI3K/Akt/mTOR PI3K
  • Create Date: 2023-10-18 11:03:55
  • Modify Date: 2024-01-22 06:03:03
  • PI3Kγ inhibitor 7 (compound 2) is a potent and orally active PI3Kγ inhibitor with IC50 values of 4768, 878.1, 3.42, 355.2 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, respectively. PI3Kγ inhibitor 7 shows antitumor activity[1].

Name PI3Kγ inhibitor 7
Description PI3Kγ inhibitor 7 (compound 2) is a potent and orally active PI3Kγ inhibitor with IC50 values of 4768, 878.1, 3.42, 355.2 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, respectively. PI3Kγ inhibitor 7 shows antitumor activity[1].
Related Catalog
Target

PI3Kα:4768 nM (IC50)

PI3Kβ:878.1 nM (IC50)

PI3Kγ:3.42 nM (IC50)

PI3Kδ:355.2 nM (IC50)

References

[1]. HeJun Lv, et al. Alkyne derivative, preparation method for same, and uses thereof. WO2021004421A1.

Molecular Formula C31H25N9O2
Molecular Weight 555.59