Pomalidomide-PEG1-NH2-1 hydrochloride

Modify Date: 2024-01-24 16:33:50

Pomalidomide-PEG1-NH2-1 hydrochloride structure	Common Name	Pomalidomide-PEG1-NH2-1 hydrochloride
	CAS Number	2380273-67-4	Molecular Weight	410.81
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₉ClN₄O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Pomalidomide-PEG1-NH2-1 hydrochloride

Pomalidomide-PEG1-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate, consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand[1].

Name	Pomalidomide-PEG1-NH2-1 hydrochloride

Description	Pomalidomide-PEG1-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate, consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
References	[1]. Lee B, et al. Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug. J Enzyme Inhib Med Chem. 2023 Dec;38(1):51-66.

Molecular Formula	C₁₇H₁₉ClN₄O₆
Molecular Weight	410.81

Pomalidomide-PEG1-NH2-1 hydrochloride

Use of Pomalidomide-PEG1-NH2-1 hydrochloride

Names

Pomalidomide-PEG1-NH2-1 hydrochloride Biological Activity

Chemical & Physical Properties