IDO1/TDO-IN-3

Modify Date: 2024-01-03 15:48:59

IDO1/TDO-IN-3 structure	Common Name	IDO1/TDO-IN-3
	CAS Number	2347579-03-5	Molecular Weight	345.69
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₆ClF₂N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of IDO1/TDO-IN-3

IDO1/TDO-IN-3 is a potent inhibitor of IDO1/TDO. IDO1/TDO-IN-3 exhibits significant activities against IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM). IDO1/TDO-IN-3 shows considerable in vivo anti-tumor activity and no obvious toxicity is observed[1].

Name	IDO1/TDO-IN-3

Description	IDO1/TDO-IN-3 is a potent inhibitor of IDO1/TDO. IDO1/TDO-IN-3 exhibits significant activities against IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM). IDO1/TDO-IN-3 shows considerable in vivo anti-tumor activity and no obvious toxicity is observed[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO)
References	[1]. Pan S, et al. Discovery and structure-activity relationship studies of 1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives as potent dual inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1) and trytophan 2,3-dioxygenase (TDO). Eur J Med Chem. 2020 Dec 1;207:112703.

Molecular Formula	C₁₆H₆ClF₂N₃O₂
Molecular Weight	345.69

IDO1/TDO-IN-3

Use of IDO1/TDO-IN-3

Names

IDO1/TDO-IN-3 Biological Activity

Chemical & Physical Properties